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Impact of Cyclooxygenase Inhibitors in the Women's Health Initiative Hormone Trials: Secondary Analysis of a Randomized Trial

OBJECTIVES: We evaluated the hypothesis that cyclooxygenase (COX) inhibitor use might have counteracted a beneficial effect of postmenopausal hormone therapy, and account for the absence of cardioprotection in the Women's Health Initiative hormone trials. Estrogen increases COX expression, and...

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Detalles Bibliográficos
Autores principales:	Hsia, Judith, Manson, JoAnn E, Kuller, Lewis, Pettinger, Mary, Choe, John H, Langer, Robert D, Limacher, Marian, Oberman, Albert, Ockene, Judith, O'Sullivan, Mary Jo, Robinson, Jennifer G
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1584256/ https://www.ncbi.nlm.nih.gov/pubmed/17016543 http://dx.doi.org/10.1371/journal.pctr.0010026

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