Gene Mutations and Genomic Rearrangements in the Mouse as a Result of Transposon Mobilization from Chromosomal Concatemers

Previous studies of the Sleeping Beauty (SB) transposon system, as an insertional mutagen in the germline of mice, have used reverse genetic approaches. These studies have led to its proposed use for regional saturation mutagenesis by taking a forward-genetic approach. Thus, we used the SB system to...

Descripción completa

Detalles Bibliográficos
Autores principales: Geurts, Aron M, Collier, Lara S, Geurts, Jennifer L, Oseth, Leann L, Bell, Matthew L, Mu, David, Lucito, Robert, Godbout, Susan A, Green, Laura E, Lowe, Scott W, Hirsch, Betsy A, Leinwand, Leslie A, Largaespada, David A
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1584263/
https://www.ncbi.nlm.nih.gov/pubmed/17009875
http://dx.doi.org/10.1371/journal.pgen.0020156

Ejemplares similares

Ejemplares similares