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Inhalation of the Rho-kinase inhibitor Y-27632 reverses allergen-induced airway hyperresponsiveness after the early and late asthmatic reaction

BACKGROUND: In guinea pigs, we have previously demonstrated that the contribution of Rho-kinase to airway responsiveness in vivo and ex vivo is enhanced after active sensitization with ovalbumin (OA). Using conscious, unrestrained OA-sensitized guina pigs, we now investigated the role of Rho-kinase...

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Detalles Bibliográficos
Autores principales:	Schaafsma, Dedmer, Bos, I Sophie T, Zuidhof, Annet B, Zaagsma, Johan, Meurs, Herman
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1586199/ https://www.ncbi.nlm.nih.gov/pubmed/17002806 http://dx.doi.org/10.1186/1465-9921-7-121

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