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Random mutagenesis in Corynebacterium glutamicum ATCC 13032 using an IS6100-based transposon vector identified the last unknown gene in the histidine biosynthesis pathway

BACKGROUND: Corynebacterium glutamicum, a Gram-positive bacterium of the class Actinobacteria, is an industrially relevant producer of amino acids. Several methods for the targeted genetic manipulation of this organism and rational strain improvement have been developed. An efficient transposon muta...

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Detalles Bibliográficos
Autores principales: Mormann, Sascha, Lömker, Alexander, Rückert, Christian, Gaigalat, Lars, Tauch, Andreas, Pühler, Alfred, Kalinowski, Jörn
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1590026/
https://www.ncbi.nlm.nih.gov/pubmed/16901339
http://dx.doi.org/10.1186/1471-2164-7-205