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Novel insights in the regulation of CCL18 secretion by monocytes and dendritic cells via cytokines, Toll-like receptors and rheumatoid synovial fluid

BACKGROUND: The T cell attracting chemokine CCL18 is produced by antigen presenting cells and a role for CCL18 has been suggested in the pathogenesis of a variety of diseases. Rheumatoid arthritis (RA) is one of these conditions, in which abundant CCL18 production is present. Although Th2 cytokines...

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Detalles Bibliográficos
Autores principales: van Lieshout, Antoine WT, van der Voort, Robbert, le Blanc, Linda MP, Roelofs, Mieke F, Schreurs, B Willem, van Riel, Piet LCM, Adema, Gosse J, Radstake, Timothy RDJ
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1590050/
https://www.ncbi.nlm.nih.gov/pubmed/16984635
http://dx.doi.org/10.1186/1471-2172-7-23