Cargando…
Mutation at the Evi1 Locus in Junbo Mice Causes Susceptibility to Otitis Media
Otitis media (OM), inflammation of the middle ear, remains the most common cause of hearing impairment in children. It is also the most common cause of surgery in children in the developed world. There is evidence from studies of the human population and mouse models that there is a significant gene...
Autores principales: | Parkinson, Nicholas, Hardisty-Hughes, Rachel E, Tateossian, Hilda, Tsai, Hsun-Tien, Brooker, Debra, Morse, Sue, Lalane, Zuzanna, MacKenzie, Francesca, Fray, Martin, Glenister, Pete, Woodward, Anne-Marie, Polley, Sian, Barbaric, Ivana, Dear, Neil, Hough, Tertius A, Hunter, A. Jackie, Cheeseman, Michael T, Brown, Steve D. M |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2006
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592239/ https://www.ncbi.nlm.nih.gov/pubmed/17029558 http://dx.doi.org/10.1371/journal.pgen.0020149 |
Ejemplares similares
-
HIF–VEGF Pathways Are Critical for Chronic Otitis Media in Junbo and Jeff Mouse Mutants
por: Cheeseman, Michael T., et al.
Publicado: (2011) -
Loss of the homeostatic protein BPIFA1, leads to exacerbation of otitis media severity in the Junbo mouse model
por: Mulay, Apoorva, et al.
Publicado: (2018) -
Regulation of TGF-β signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant
por: Tateossian, Hilda, et al.
Publicado: (2009) -
A new model for non-typeable Haemophilus influenzae middle ear infection in the Junbo mutant mouse
por: Hood, Derek, et al.
Publicado: (2016) -
Otitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease
por: Tateossian, Hilda, et al.
Publicado: (2013)