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Combining genetic and biochemical approaches to identify functional molecular contact points

Protein-protein interactions are required for many viral and cellular functions and are potential targets for novel therapies. Here we detail a series of genetic and biochemical techniques used in combination to find an essential molecular contact point on the duck hepatitis B virus polymerase. Thes...

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Detalles Bibliográficos
Autores principales: Badtke, Matthew P., Cao, Feng, Tavis, John E.
Formato: Texto
Lenguaje:English
Publicado: Biological Procedures Online 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592461/
https://www.ncbi.nlm.nih.gov/pubmed/17033698
http://dx.doi.org/10.1251/bpo121