Asymmetric aza-Diels-Alder reaction of Danishefsky's diene with imines in a chiral reaction medium

The asymmetric aza-Diels-Alder reaction of chiral imines with Danishefsky's diene in chiral ionic liquids provides the corresponding cycloadduct with moderate to high diastereoselectivity. The reaction has proved to perform better at room temperature in ionic liquids without either Lewis acid c...

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Detalles Bibliográficos
Autores principales: Pégot, Bruce, Van Buu, Olivier Nguyen, Gori, Didier, Vo-Thanh, Giang
Formato: Texto
Lenguaje:English
Publicado: Beilstein-Institut 2006
Materias:
Preliminary Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592496/
https://www.ncbi.nlm.nih.gov/pubmed/16982000
http://dx.doi.org/10.1186/1860-5397-2-18
Descripción
Sumario:The asymmetric aza-Diels-Alder reaction of chiral imines with Danishefsky's diene in chiral ionic liquids provides the corresponding cycloadduct with moderate to high diastereoselectivity. The reaction has proved to perform better at room temperature in ionic liquids without either Lewis acid catalyst or organic solvent. Chiral ionic liquids are recycled while their efficiency is preserved.

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