Functional expression of a single-chain antibody to ErbB-2 in plants and cell-free systems

BACKGROUND: Aberrant signaling by ErbB-2 (HER 2, Neu), a member of the human Epidermal Growth Factor (EGF) receptor family, is associated with an aggressive clinical behaviour of carcinomas, particularly breast tumors. Antibodies targeting the ErbB-2 pathway are a preferred therapeutic option for pa...

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Detalles Bibliográficos
Autores principales: Galeffi, Patrizia, Lombardi, Alessio, Pietraforte, Immacolata, Novelli, Flavia, Di Donato, Monica, Sperandei, Maria, Tornambé, Andrea, Fraioli, Rocco, Martayan, Aline, Natali, Pier Giorgio, Benevolo, Maria, Mottolese, Marcella, Ylera, Francisco, Cantale, Cristina, Giacomini, Patrizio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592514/
https://www.ncbi.nlm.nih.gov/pubmed/17010186
http://dx.doi.org/10.1186/1479-5876-4-39

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