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Two Plasmodium Rhomboid Proteases Preferentially Cleave Different Adhesins Implicated in All Invasive Stages of Malaria

Invasion of host cells by the malaria pathogen Plasmodium relies on parasite transmembrane adhesins that engage host-cell receptors. Adhesins must be released by cleavage before the parasite can enter the cell, but the processing enzymes have remained elusive. Recent work indicates that the Toxoplas...

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Detalles Bibliográficos
Autores principales: Baker, Rosanna P, Wijetilaka, Ruvini, Urban, Sinisa
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1599764/
https://www.ncbi.nlm.nih.gov/pubmed/17040128
http://dx.doi.org/10.1371/journal.ppat.0020113