Large-Scale Turnover of Functional Transcription Factor Binding Sites in Drosophila

The gain and loss of functional transcription factor binding sites has been proposed as a major source of evolutionary change in cis-regulatory DNA and gene expression. We have developed an evolutionary model to study binding-site turnover that uses multiple sequence alignments to assess the evoluti...

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Detalles Bibliográficos
Autores principales: Moses, Alan M, Pollard, Daniel A, Nix, David A, Iyer, Venky N, Li, Xiao-Yong, Biggin, Mark D, Eisen, Michael B
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1599766/
https://www.ncbi.nlm.nih.gov/pubmed/17040121
http://dx.doi.org/10.1371/journal.pcbi.0020130

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