Short G-rich oligonucleotides as a potential therapeutic for Huntington's Disease

BACKGROUND: Huntington's Disease (HD) is an inherited autosomal dominant genetic disorder in which neuronal tissue degenerates. The pathogenesis of the disease appears to center on the development of protein aggregates that arise initially from the misfolding of the mutant HD protein. Mutant hu...

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Detalles Bibliográficos
Autores principales: Skogen, Michael, Roth, Jennifer, Yerkes, Sarah, Parekh-Olmedo, Hetal, Kmiec, Eric
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1609172/
https://www.ncbi.nlm.nih.gov/pubmed/17014717
http://dx.doi.org/10.1186/1471-2202-7-65

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1609172/
https://www.ncbi.nlm.nih.gov/pubmed/17014717
http://dx.doi.org/10.1186/1471-2202-7-65

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