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Short G-rich oligonucleotides as a potential therapeutic for Huntington's Disease
BACKGROUND: Huntington's Disease (HD) is an inherited autosomal dominant genetic disorder in which neuronal tissue degenerates. The pathogenesis of the disease appears to center on the development of protein aggregates that arise initially from the misfolding of the mutant HD protein. Mutant hu...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1609172/ https://www.ncbi.nlm.nih.gov/pubmed/17014717 http://dx.doi.org/10.1186/1471-2202-7-65 |