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Anthrax Toxin Receptor 2–Dependent Lethal Toxin Killing In Vivo

Anthrax toxin receptors 1 and 2 (ANTXR1 and ANTXR2) have a related integrin-like inserted (I) domain which interacts with a metal cation that is coordinated by residue D683 of the protective antigen (PA) subunit of anthrax toxin. The receptor-bound metal ion and PA residue D683 are critical for ANTX...

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Detalles Bibliográficos
Autores principales: Scobie, Heather M, Wigelsworth, Darran J, Marlett, John M, Thomas, Diane, Rainey, G. Jonah A, Lacy, D. Borden, Manchester, Marianne, Collier, R. John, Young, John A. T
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1617126/
https://www.ncbi.nlm.nih.gov/pubmed/17054395
http://dx.doi.org/10.1371/journal.ppat.0020111