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Structural basis of regulation and substrate specificity of protein kinase CK2 deduced from the modeling of protein-protein interactions

BACKGROUND: Protein Kinase Casein Kinase 2 (PKCK2) is an ubiquitous Ser/Thr kinase expressed in all eukaryotes. It phosphorylates a number of proteins involved in various cellular processes. PKCK2 holoenzyme is catalytically active tetramer, composed of two homologous or identical and constitutively...

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Detalles Bibliográficos
Autores principales: Rekha, Nambudiry, Srinivasan, N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC161795/
https://www.ncbi.nlm.nih.gov/pubmed/12740046
http://dx.doi.org/10.1186/1472-6807-3-4

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