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Genetic analysis of the GRIK2 modifier effect in Huntington's disease
BACKGROUND: In Huntington's disease (HD), age at neurological onset is inversely correlated with the length of the CAG trinucleotide repeat mutation, but can be modified by genetic factors beyond the HD gene. Association of a relatively infrequent 16 TAA allele of a trinucleotide repeat polymor...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618398/ https://www.ncbi.nlm.nih.gov/pubmed/16959037 http://dx.doi.org/10.1186/1471-2202-7-62 |