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Genetic analysis of the GRIK2 modifier effect in Huntington's disease

BACKGROUND: In Huntington's disease (HD), age at neurological onset is inversely correlated with the length of the CAG trinucleotide repeat mutation, but can be modified by genetic factors beyond the HD gene. Association of a relatively infrequent 16 TAA allele of a trinucleotide repeat polymor...

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Detalles Bibliográficos
Autores principales:	Zeng, Wenqi, Gillis, Tammy, Hakky, Michael, Djoussé, Luc, Myers, Richard H, MacDonald, Marcy E, Gusella, James F
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618398/ https://www.ncbi.nlm.nih.gov/pubmed/16959037 http://dx.doi.org/10.1186/1471-2202-7-62

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