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Microarray analysis after RNA amplification can detect pronounced differences in gene expression using limma
BACKGROUND: RNA amplification is necessary for profiling gene expression from small tissue samples. Previous studies have shown that the T7 based amplification techniques are reproducible but may distort the true abundance of targets. However, the consequences of such distortions on the ability to d...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618401/ https://www.ncbi.nlm.nih.gov/pubmed/17029630 http://dx.doi.org/10.1186/1471-2164-7-252 |