Searching for interpretable rules for disease mutations: a simulated annealing bump hunting strategy

BACKGROUND: Understanding how amino acid substitutions affect protein functions is critical for the study of proteins and their implications in diseases. Although methods have been developed for predicting potential effects of amino acid substitutions using sequence, three-dimensional structural, an...

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Detalles Bibliográficos
Autores principales: Jiang, Rui, Yang, Hua, Sun, Fengzhu, Chen, Ting
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618409/
https://www.ncbi.nlm.nih.gov/pubmed/16984653
http://dx.doi.org/10.1186/1471-2105-7-417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618409/
https://www.ncbi.nlm.nih.gov/pubmed/16984653
http://dx.doi.org/10.1186/1471-2105-7-417

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