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Searching for interpretable rules for disease mutations: a simulated annealing bump hunting strategy
BACKGROUND: Understanding how amino acid substitutions affect protein functions is critical for the study of proteins and their implications in diseases. Although methods have been developed for predicting potential effects of amino acid substitutions using sequence, three-dimensional structural, an...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618409/ https://www.ncbi.nlm.nih.gov/pubmed/16984653 http://dx.doi.org/10.1186/1471-2105-7-417 |