Cargando…

Ligand Valency Affects Transcytosis, Recycling and Intracellular Trafficking Mediated by the Neonatal Fc Receptor

The neonatal Fc receptor (FcRn) transports IgG across epithelial cell barriers to provide maternal antibodies to offspring and serves as a protection receptor by rescuing endocytosed IgG and albumin from lysosomal degradation. Here we describe the generation of polarized Madin–Darby canine kidney (M...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tesar, Devin B, Tiangco, Noreen E, Bjorkman, Pamela J
Formato:	Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2006
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618808/ https://www.ncbi.nlm.nih.gov/pubmed/17004319 http://dx.doi.org/10.1111/j.1600-0854.2006.00457.x

Ejemplares similares

Electron tomography of late stages of FcRn-mediated antibody transcytosis in neonatal rat small intestine
por: Ladinsky, Mark S., et al.
Publicado: (2012)

Transcytosis of HIV-1 through Vaginal Epithelial Cells Is Dependent on Trafficking to the Endocytic Recycling Pathway
por: Kinlock, Ballington L., et al.
Publicado: (2014)

The FcεRI signaling cascade and integrin trafficking converge at patterned ligand surfaces
por: Wakefield, Devin L., et al.
Publicado: (2017)

The Neonatal Fc Receptor (FcRn) Enhances Human Immunodeficiency Virus Type 1 (HIV-1) Transcytosis across Epithelial Cells
por: Gupta, Sandeep, et al.
Publicado: (2013)

An in vitro FcRn- dependent transcytosis assay as a screening tool for predictive assessment of nonspecific clearance of antibody therapeutics in humans
por: Chung, Shan, et al.
Publicado: (2019)

Correction: The Neonatal Fc Receptor (FcRn) Enhances Human Immunodeficiency Virus Type 1 (HIV-1) Transcytosis across Epithelial Cells
por: Gupta, Sandeep, et al.
Publicado: (2013)

Human and Non-Human Primate Intestinal FcRn Expression and Immunoglobulin G Transcytosis
por: Hornby, Pamela J., et al.
Publicado: (2013)

Intracellular Trafficking Considerations in the Development of Natural Ligand-Drug Molecular Conjugates for Cancer
por: Yoon, Dennis J., et al.
Publicado: (2011)

Comparison of FcRn- and pIgR-Mediated Transport in MDCK Cells by Fluorescence Confocal Microscopy
por: Jerdeva, Galina V, et al.
Publicado: (2010)

Activation of the JNK/MAPK Signaling Pathway by TGF-β1 Enhances Neonatal Fc Receptor Expression and IgG Transcytosis
por: Qian, Shaoju, et al.
Publicado: (2021)

Intracellular transport and regulation of transcytosis across the blood–brain barrier
por: Villaseñor, Roberto, et al.
Publicado: (2018)

Dynamics of intracellular neonatal Fc receptor–ligand interactions in primary macrophages using biophysical fluorescence techniques
por: Pannek, Andreas, et al.
Publicado: (2022)

Phorbol myristate acetate-mediated stimulation of transcytosis and apical recycling in MDCK cells
Publicado: (1994)

Antibody transcytosis across brain endothelial-like cells occurs nonspecifically and independent of FcRn
por: Ruano-Salguero, John S., et al.
Publicado: (2020)

Receptor-mediated transcytosis of IgA in MDCK cells is via apical recycling endosomes
Publicado: (1994)

Regulation of ligand-independent Notch signal through intracellular trafficking
por: Hori, Kazuya, et al.
Publicado: (2012)

Endocytic recycling and vesicular transport systems mediate transcytosis of Leptospira interrogans across cell monolayer
por: Li, Yang, et al.
Publicado: (2019)

The Role of Intracellular Trafficking of Notch Receptors in Ligand-Independent Notch Activation
por: Hounjet, Judith, et al.
Publicado: (2021)

The Arp2/3 complex has essential roles in vesicle trafficking and transcytosis in the mammalian small intestine
por: Zhou, Kang, et al.
Publicado: (2015)

Subcellular trafficking and transcytosis efficacy of different receptor types for therapeutic antibody delivery at the blood‒brain barrier
por: Holst, Mikkel Roland, et al.
Publicado: (2023)

Subliminal Affect Valence Words Change Conscious Mood Potency but Not Valence: Is This Evidence for Unconscious Valence Affect?
por: Shevrin, Howard, et al.
Publicado: (2012)

Differential trafficking of albumin and IgG facilitated by the neonatal Fc receptor in podocytes in vitro and in vivo
por: Dylewski, James, et al.
Publicado: (2019)

Knockout of the neonatal Fc receptor alters immune complex trafficking and lysosomal function in cultured podocytes
por: Haddad, George, et al.
Publicado: (2023)

Polarized α-synuclein trafficking and transcytosis across brain endothelial cells via Rab7-decorated carriers
por: Alam, Parvez, et al.
Publicado: (2022)

Micro-Valences: Perceiving Affective Valence in Everyday Objects
por: Lebrecht, Sophie, et al.
Publicado: (2012)

Reduced FcRn-mediated transcytosis of IgG2 due to a missing Glycine in its lower hinge
por: Stapleton, Nigel M., et al.
Publicado: (2019)

Regulation of Fc Receptor Endocytic Trafficking by Ubiquitination
por: Molfetta, Rosa, et al.
Publicado: (2014)

Megalin Orchestrates FcRn Endocytosis and Trafficking
por: Dahlke, Eileen, et al.
Publicado: (2022)

Transcytosis in the blood–cerebrospinal fluid barrier of the mouse brain with an engineered receptor/ligand system
por: Méndez-Gómez, Héctor R, et al.
Publicado: (2015)

Quantitative cumulative biodistribution of antibodies in mice: Effect of modulating binding affinity to the neonatal Fc receptor
por: Yip, Victor, et al.
Publicado: (2014)

Transcytosis in thyroid follicle cells
Publicado: (1983)

Transcytosis of albumin in capillary endothelium
Publicado: (1987)

Transcytosis of Staphylococcal Superantigen Toxins
por: Hamad, Abdel Rahim A., et al.
Publicado: (1997)

Endocytosis and transcytosis of gliadin peptides
por: Barone, M. Vittoria, et al.
Publicado: (2016)

Endothelial Transcytosis of Lipoproteins in Atherosclerosis
por: Zhang, Xinbo, et al.
Publicado: (2018)

Crystal Structure of the HSV-1 Fc Receptor Bound to Fc Reveals a Mechanism for Antibody Bipolar Bridging
por: Sprague, Elizabeth R, et al.
Publicado: (2006)

Parameter Identification for a Model of Neonatal Fc Receptor-Mediated Recycling of Endogenous Immunoglobulin G in Humans
por: Kendrick, Felicity, et al.
Publicado: (2019)

Protocol for measuring transcytosis and recycling of IgG in intestinal epithelial Caco-2 cells and primary human intestinal organoids
por: Maeda, Keiko, et al.
Publicado: (2023)

Intracellular trafficking and signaling in development
por: Constam, Daniel B
Publicado: (2009)

Intracellular Trafficking of HBV Particles
por: Jiang, Bingfu, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_6h7vhi77e4buf0r691nimvrtld