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Expression and loss of alleles in cultured mouse embryonic fibroblasts and stem cells carrying allelic fluorescent protein genes

BACKGROUND: Loss of heterozygosity (LOH) contributes to many cancers, but the rate at which these events occur in normal cells of the body is not clear. LOH would be detectable in diverse cell types in the body if this event were to confer an obvious cellular phenotype. Mice that carry two different...

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Detalles Bibliográficos
Autores principales: Larson, Jon S, Yin, Moying, Fischer, Jared M, Stringer, Saundra L, Stringer, James R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1621078/
https://www.ncbi.nlm.nih.gov/pubmed/17042952
http://dx.doi.org/10.1186/1471-2199-7-36