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Expression and loss of alleles in cultured mouse embryonic fibroblasts and stem cells carrying allelic fluorescent protein genes
BACKGROUND: Loss of heterozygosity (LOH) contributes to many cancers, but the rate at which these events occur in normal cells of the body is not clear. LOH would be detectable in diverse cell types in the body if this event were to confer an obvious cellular phenotype. Mice that carry two different...
Autores principales: | Larson, Jon S, Yin, Moying, Fischer, Jared M, Stringer, Saundra L, Stringer, James R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1621078/ https://www.ncbi.nlm.nih.gov/pubmed/17042952 http://dx.doi.org/10.1186/1471-2199-7-36 |
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