Effect of Reparation of Repeat Sequences in the Human α-Synuclein on Fibrillation Ability

The aggregation and fibrillation of α-synuclein has been implicated as a causative factor in the Parkinson's disease. The hexamer motif KTKEGV is found in each of the seven imperfect repeat sequences in the N-terminal half of α-synuclein. The motif is not fully conserved in the sixth and sevent...

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Detalles Bibliográficos
Autores principales: Sode, Koji, Ochiai, Sayaka, Kobayashi, Natsuki, Usuzaka, Eri
Formato: Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2006
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1622890/
https://www.ncbi.nlm.nih.gov/pubmed/17200685

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