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TILLING is an effective reverse genetics technique for Caenorhabditis elegans

BACKGROUND: TILLING (Targeting Induced Local Lesions in Genomes) is a reverse genetic technique based on the use of a mismatch-specific enzyme that identifies mutations in a target gene through heteroduplex analysis. We tested this technique in Caenorhabditis elegans, a model organism in which genom...

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Detalles Bibliográficos
Autores principales:	Gilchrist, Erin J, O'Neil, Nigel J, Rose, Ann M, Zetka, Monique C, Haughn, George W
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1626091/ https://www.ncbi.nlm.nih.gov/pubmed/17049087 http://dx.doi.org/10.1186/1471-2164-7-262

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