EC(5)S Ubiquitin Complex Is Recruited by KSHV Latent Antigen LANA for Degradation of the VHL and p53 Tumor Suppressors

Cellular protein degradation pathways can be utilized by viruses to establish an environment that favors their propagation. Here we report that the Kaposi's sarcoma–associated herpesvirus (KSHV)-encoded latency-associated nuclear antigen (LANA) directly functions as a component of the EC(5)S ub...

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Detalles Bibliográficos
Autores principales: Cai, Qi-Liang, Knight, Jason S, Verma, Suhbash C, Zald, Philip, Robertson, Erle S
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1626105/
https://www.ncbi.nlm.nih.gov/pubmed/17069461
http://dx.doi.org/10.1371/journal.ppat.0020116

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