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The matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts
Integrin-mediated cell adhesion to extracellular matrix proteins is known to promote cell survival, whereas detachment from the matrix can cause rapid apoptotic death in some cell types. Contrary to this paradigm, we show that fibroblast adhesion to the angiogenic matrix protein CCN1 (CYR61) induces...
Autores principales: | Todorovicç, Viktor, Chen, Chih-Chiun, Hay, Nissim, Lau, Lester F. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1626352/ https://www.ncbi.nlm.nih.gov/pubmed/16275757 http://dx.doi.org/10.1083/jcb.200504015 |
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