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HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response against HIV-1

BACKGROUND: Very little is known about the immunodominance patterns of HIV-1-specific T cell responses during primary HIV-1 infection and the reasons for human lymphocyte antigen (HLA) modulation of disease progression. METHODS AND FINDINGS: In a cohort of 104 individuals with primary HIV-1 infectio...

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Detalles Bibliográficos
Autores principales: Altfeld, Marcus, Kalife, Elizabeth T, Qi, Ying, Streeck, Hendrik, Lichterfeld, Mathias, Johnston, Mary N, Burgett, Nicole, Swartz, Martha E, Yang, Amy, Alter, Galit, Yu, Xu G, Meier, Angela, Rockstroh, Juergen K, Allen, Todd M, Jessen, Heiko, Rosenberg, Eric S, Carrington, Mary, Walker, Bruce D
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1626551/
https://www.ncbi.nlm.nih.gov/pubmed/17076553
http://dx.doi.org/10.1371/journal.pmed.0030403