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Evaluation of the activity of CYP2C19 in Gujrati and Marwadi subjects living in Mumbai (Bombay)
BACKGROUND: Inherited differences in the metabolism and disposition of drugs, and genetic polymorphisms in the targets of drug therapy (e.g., receptors), can greatly influence efficacy and toxicity of medications. Marked interethnic differences in CYP2C19 (a member of the cytochrome P-450 enzyme sup...
Autores principales: | Panchabhai, Tanmay S, Noronha, Shaun F, Davis, Sanish, Shinde, Vishal M, Kshirsagar, Nilima A, Gogtay, Nithya J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1630702/ https://www.ncbi.nlm.nih.gov/pubmed/17062149 http://dx.doi.org/10.1186/1472-6904-6-8 |
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