Adaptation to ER Stress Is Mediated by Differential Stabilities of Pro-Survival and Pro-Apoptotic mRNAs and Proteins

The accumulation of unfolded proteins in the endoplasmic reticulum (ER) activates a signaling cascade known as the unfolded protein response (UPR). Although activation of the UPR is well described, there is little sense of how the response, which initiates both apoptotic and adaptive pathways, can s...

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Detalles Bibliográficos
Autores principales: Rutkowski, D. Thomas, Arnold, Stacey M, Miller, Corey N, Wu, Jun, Li, Jack, Gunnison, Kathryn M, Mori, Kazutoshi, Sadighi Akha, Amir A., Raden, David, Kaufman, Randal J
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1634883/
https://www.ncbi.nlm.nih.gov/pubmed/17090218
http://dx.doi.org/10.1371/journal.pbio.0040374

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