HIV infection of non-dividing cells: a divisive problem

Understanding how lentiviruses can infect terminally differentiated, non-dividing cells has proven a very complex and controversial problem. It is, however, a problem worth investigating, for it is central to HIV-1 transmission and AIDS pathogenesis. Here I shall attempt to summarise what is our cur...

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Detalles Bibliográficos
Autor principal: Fassati, Ariberto
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635064/
https://www.ncbi.nlm.nih.gov/pubmed/17067381
http://dx.doi.org/10.1186/1742-4690-3-74
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author Fassati, Ariberto
author_facet Fassati, Ariberto
author_sort Fassati, Ariberto
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description Understanding how lentiviruses can infect terminally differentiated, non-dividing cells has proven a very complex and controversial problem. It is, however, a problem worth investigating, for it is central to HIV-1 transmission and AIDS pathogenesis. Here I shall attempt to summarise what is our current understanding for HIV-1 infection of non-dividing cells. In some cases I shall also attempt to make sense of controversies in the field and advance one or two modest proposals.
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spelling pubmed-16350642006-11-08 HIV infection of non-dividing cells: a divisive problem Fassati, Ariberto Retrovirology Review Understanding how lentiviruses can infect terminally differentiated, non-dividing cells has proven a very complex and controversial problem. It is, however, a problem worth investigating, for it is central to HIV-1 transmission and AIDS pathogenesis. Here I shall attempt to summarise what is our current understanding for HIV-1 infection of non-dividing cells. In some cases I shall also attempt to make sense of controversies in the field and advance one or two modest proposals. BioMed Central 2006-10-26 /pmc/articles/PMC1635064/ /pubmed/17067381 http://dx.doi.org/10.1186/1742-4690-3-74 Text en Copyright © 2006 Fassati; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Fassati, Ariberto
HIV infection of non-dividing cells: a divisive problem
title HIV infection of non-dividing cells: a divisive problem
title_full HIV infection of non-dividing cells: a divisive problem
title_fullStr HIV infection of non-dividing cells: a divisive problem
title_full_unstemmed HIV infection of non-dividing cells: a divisive problem
title_short HIV infection of non-dividing cells: a divisive problem
title_sort hiv infection of non-dividing cells: a divisive problem
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635064/
https://www.ncbi.nlm.nih.gov/pubmed/17067381
http://dx.doi.org/10.1186/1742-4690-3-74
work_keys_str_mv AT fassatiariberto hivinfectionofnondividingcellsadivisiveproblem

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