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The bipartite architecture of the sRNA in an archaeal box C/D complex is a primary determinant of specificity

The archaeal box C/D sRNP, the enzyme responsible for 2′-O-methylation of rRNA and tRNA, possesses a nearly perfect axis of symmetry and bipartite structure. This RNP contains two platforms for the assembly of protein factors, the C/D and C′/D′ motifs, acting in conjunction with two guide sequences...

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Detalles Bibliográficos
Autores principales: Hardin, John W., Batey, Robert T.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635284/
https://www.ncbi.nlm.nih.gov/pubmed/16984968
http://dx.doi.org/10.1093/nar/gkl644