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Binding of human SLBP on the 3′-UTR of histone precursor H4-12 mRNA induces structural rearrangements that enable U7 snRNA anchoring

In metazoans, cell-cycle-dependent histones are produced from poly(A)-lacking mRNAs. The 3′ end of histone mRNAs is formed by an endonucleolytic cleavage of longer precursors between a conserved stem–loop structure and a purine-rich histone downstream element (HDE). The cleavage requires at least tw...

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Detalles Bibliográficos
Autores principales:	Jaeger, Sophie, Martin, Franck, Rudinger-Thirion, Joëlle, Giegé, Richard, Eriani, Gilbert
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2006
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635294/ https://www.ncbi.nlm.nih.gov/pubmed/16982637 http://dx.doi.org/10.1093/nar/gkl666

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