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Human RECQ5β helicase promotes strand exchange on synthetic DNA structures resembling a stalled replication fork

The role of the human RECQ5β helicase in the maintenance of genomic stability remains elusive. Here we show that RECQ5β promotes strand exchange between arms of synthetic forked DNA structures resembling a stalled replication fork in a reaction dependent on ATP hydrolysis. BLM and WRN can also promo...

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Detalles Bibliográficos
Autores principales: Kanagaraj, Radhakrishnan, Saydam, Nurten, Garcia, Patrick L., Zheng, Lu, Janscak, Pavel
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635296/
https://www.ncbi.nlm.nih.gov/pubmed/17003056
http://dx.doi.org/10.1093/nar/gkl677

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