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Antibody binding loop insertions as diversity elements
In the use of non-antibody proteins as affinity reagents, diversity has generally been derived from oligonucleotide-encoded random amino acids. Although specific binders of high-affinity have been selected from such libraries, random oligonucleotides often encode stop codons and amino acid combinati...
Autores principales: | Kiss, Csaba, Fisher, Hugh, Pesavento, Emanuele, Dai, Minghua, Valero, Rosa, Ovecka, Milan, Nolan, Rhiannon, Phipps, M. Lisa, Velappan, Nileena, Chasteen, Leslie, Martinez, Jennifer S., Waldo, Geoffrey S., Pavlik, Peter, Bradbury, Andrew R.M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635297/ https://www.ncbi.nlm.nih.gov/pubmed/17023486 http://dx.doi.org/10.1093/nar/gkl681 |
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