PIAS3 induction of PRB sumoylation represses PRB transactivation by destabilizing its retention in the nucleus

Progesterone receptor (PR) plays a critical role in cell proliferation and differentiation, and its transcriptional activity is known to be modulated by cofactor proteins. In the present study, we demonstrated that in the presence of progesterone, protein inhibitor of activated STAT-3 (PIAS3) signif...

Descripción completa

Detalles Bibliográficos
Autores principales: Man, Jiang-Hong, Li, Hui-Yan, Zhang, Pei-Jing, Zhou, Tao, He, Kun, Pan, Xin, Liang, Bing, Li, Ai-Ling, Zhao, Jie, Gong, Wei-Li, Jin, Bao-Feng, Xia, Qing, Yu, Ming, Shen, Bei-Fen, Zhang, Xue-Min
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635300/
https://www.ncbi.nlm.nih.gov/pubmed/17020914
http://dx.doi.org/10.1093/nar/gkl691

Ejemplares similares

Ejemplares similares