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Limiting amounts of budding yeast Rad53 S-phase checkpoint activity results in increased resistance to DNA alkylation damage

The Saccharomyces cerevisiae protein kinase Rad53 plays a key role in maintaining genomic integrity after DNA damage and is an essential component of the ‘intra-S-phase checkpoint’. In budding yeast, alkylating chemicals, such as methyl methanesulfonate (MMS), or depletion of nucleotides by hydroxyu...

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Detalles Bibliográficos
Autores principales:	Cordón-Preciado, Violeta, Ufano, Sandra, Bueno, Avelino
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2006
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635317/ https://www.ncbi.nlm.nih.gov/pubmed/17062626 http://dx.doi.org/10.1093/nar/gkl741

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