Cargando…

Drug-induced activation of SREBP-controlled lipogenic gene expression in CNS-related cell lines: Marked differences between various antipsychotic drugs

BACKGROUND: The etiology of schizophrenia is unknown, but neurodevelopmental disturbances, myelin- and oligodendrocyte abnormalities and synaptic dysfunction have been suggested as pathophysiological factors in this severe psychiatric disorder. Cholesterol is an essential component of myelin and has...

Descripción completa

Detalles Bibliográficos
Autores principales: Fernø, Johan, Skrede, Silje, Vik-Mo, Audun O, Håvik, Bjarte, Steen, Vidar M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635424/
https://www.ncbi.nlm.nih.gov/pubmed/17052361
http://dx.doi.org/10.1186/1471-2202-7-69