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The Role of DNA Double-Strand Breaks in Spontaneous Homologous Recombination in S. cerevisiae
Homologous recombination (HR) is a source of genomic instability and the loss of heterozygosity in mitotic cells. Since these events pose a severe health risk, it is important to understand the molecular events that cause spontaneous HR. In eukaryotes, high levels of HR are a normal feature of meios...
Autores principales: | Lettier, Gaëlle, Feng, Qi, de Mayolo, Adriana Antúnez, Erdeniz, Naz, Reid, Robert J. D, Lisby, Michael, Mortensen, Uffe H, Rothstein, Rodney |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635536/ https://www.ncbi.nlm.nih.gov/pubmed/17096599 http://dx.doi.org/10.1371/journal.pgen.0020194 |
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