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Dendritic cell-mediated HIV-1 transmission to T cells of LAD-1 patients is impaired due to the defect in LFA-1

BACKGROUND: Dendritic cells (DC) have been proposed to mediate sexual HIV-1 transmission by capturing the virus in the mucosa and subsequently presenting it to CD4(+ )T cells. We have demonstrated before that DC subsets expressing higher levels of intercellular adhesion molecule-1 (ICAM-1) are bette...

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Detalles Bibliográficos
Autores principales:	Groot, Fedde, Kuijpers, Taco W, Berkhout, Ben, de Jong, Esther C
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635562/ https://www.ncbi.nlm.nih.gov/pubmed/17078873 http://dx.doi.org/10.1186/1742-4690-3-75

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