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Effects of TGF-β1 and IGF-1 on proliferation of human nucleus pulposus cells in medium with different serum concentrations

BACKGROUND: The low proliferative viability of human nucleus pulposus(NP) cells is considered as a cause of intervertebral discs degeneration. Growth factors, such as TGF-β1 and IGF-1, have been implicated in cell proliferation and matrix synthesis. OBJECTIVE: To investigate the dose-response and ti...

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Detalles Bibliográficos
Autores principales: Zhang, Rongfeng, Ruan, Dike, Zhang, Chao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636034/
https://www.ncbi.nlm.nih.gov/pubmed/17150129
http://dx.doi.org/10.1186/1749-799X-1-9