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Estrogen protects neuronal cells from amyloid beta-induced apoptosis via regulation of mitochondrial proteins and function

BACKGROUND: Neurodegeneration in Alzheimer's disease is associated with increased apoptosis and parallels increased levels of amyloid beta, which can induce neuronal apoptosis. Estrogen exposure prior to neurotoxic insult of hippocampal neurons promotes neuronal defence and survival against neu...

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Detalles Bibliográficos
Autores principales: Nilsen, Jon, Chen, Shuhua, Irwin, Ronald W, Iwamoto, Sean, Brinton, Roberta Diaz
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636062/
https://www.ncbi.nlm.nih.gov/pubmed/17083736
http://dx.doi.org/10.1186/1471-2202-7-74

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