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Estrogen protects neuronal cells from amyloid beta-induced apoptosis via regulation of mitochondrial proteins and function
BACKGROUND: Neurodegeneration in Alzheimer's disease is associated with increased apoptosis and parallels increased levels of amyloid beta, which can induce neuronal apoptosis. Estrogen exposure prior to neurotoxic insult of hippocampal neurons promotes neuronal defence and survival against neu...
Autores principales: | Nilsen, Jon, Chen, Shuhua, Irwin, Ronald W, Iwamoto, Sean, Brinton, Roberta Diaz |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636062/ https://www.ncbi.nlm.nih.gov/pubmed/17083736 http://dx.doi.org/10.1186/1471-2202-7-74 |
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