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A specific loop in human DNA polymerase mu allows switching between creative and DNA-instructed synthesis

Human DNA polymerase mu (Polμ) is a family X member that has terminal transferase activity but, in spite of a non-orthodox selection of the template information, displays its maximal catalytic efficiency in DNA-templated reactions. As terminal deoxynucleotidyl transferase (TdT), Polμ has a specific...

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Detalles Bibliográficos
Autores principales:	Juárez, Raquel, Ruiz, José F., McElhinny, Stephanie A. Nick, Ramsden, Dale, Blanco, Luis
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2006
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636348/ https://www.ncbi.nlm.nih.gov/pubmed/16963491 http://dx.doi.org/10.1093/nar/gkl457

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