Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing

DGCR8/Pasha is an essential cofactor for Drosha, a nuclear RNase III that cleaves the local hairpin structures embedded in long primary microRNA transcripts (pri-miRNAs) in eukaryotes. Although our knowledge of pri-miRNA processing has significantly advanced in recent years, the precise role of DGCR...

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Detalles Bibliográficos
Autores principales: Yeom, Kyu-Hyeon, Lee, Yoontae, Han, Jinju, Suh, Mi Ra, Kim, V. Narry
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636349/
https://www.ncbi.nlm.nih.gov/pubmed/16963499
http://dx.doi.org/10.1093/nar/gkl458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636349/
https://www.ncbi.nlm.nih.gov/pubmed/16963499
http://dx.doi.org/10.1093/nar/gkl458

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