Tumor inhibition by genomically integrated inducible RNAi-cassettes

RNA interference (RNAi) has emerged as a powerful tool to induce loss-of-function phenotypes by post-transcriptional silencing of gene expression. In this study we wondered whether inducible RNAi-cassettes integrated into cellular DNA possess the power to trigger neoplastic growth. For this purpose...

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Detalles Bibliográficos
Autores principales: Kappel, Sven, Matthess, Yves, Zimmer, Brigitte, Kaufmann, Manfred, Strebhardt, Klaus
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636372/
https://www.ncbi.nlm.nih.gov/pubmed/16945954
http://dx.doi.org/10.1093/nar/gkl628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636372/
https://www.ncbi.nlm.nih.gov/pubmed/16945954
http://dx.doi.org/10.1093/nar/gkl628

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