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Tumor inhibition by genomically integrated inducible RNAi-cassettes
RNA interference (RNAi) has emerged as a powerful tool to induce loss-of-function phenotypes by post-transcriptional silencing of gene expression. In this study we wondered whether inducible RNAi-cassettes integrated into cellular DNA possess the power to trigger neoplastic growth. For this purpose...
Autores principales: | Kappel, Sven, Matthess, Yves, Zimmer, Brigitte, Kaufmann, Manfred, Strebhardt, Klaus |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636372/ https://www.ncbi.nlm.nih.gov/pubmed/16945954 http://dx.doi.org/10.1093/nar/gkl628 |
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