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NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region

BCL2 protein functions as an inhibitor of cell apoptosis and has been found to be aberrantly expressed in a wide range of human diseases. A highly GC-rich region upstream of the P1 promoter plays an important role in the transcriptional regulation of BCL2. Here we report the NMR solution structure o...

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Detalles Bibliográficos
Autores principales:	Dai, Jixun, Chen, Ding, Jones, Roger A., Hurley, Laurence H., Yang, Danzhou
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2006
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636422/ https://www.ncbi.nlm.nih.gov/pubmed/16998187 http://dx.doi.org/10.1093/nar/gkl610

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