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Assessing incomplete deprotection of microarray oligonucleotides in situ
En masse analysis of gene structure and function by array technologies will have a lasting and profound effect on biology and medicine. This impact can be compromised by low quality of probes within arrays, which we show can be caused by incomplete removal of chemical protecting groups. To solve thi...
Autores principales: | Dressman, Holly K., Barley-Maloney, Lise, Rowlette, Laura-Leigh, Agris, Paul F., Garcia-Blanco, Mariano A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636491/ https://www.ncbi.nlm.nih.gov/pubmed/17020916 http://dx.doi.org/10.1093/nar/gkl713 |
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