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Evolutionarily conserved and non-conserved retrovirus restriction activities of artiodactyl APOBEC3F proteins

The APOBEC3 proteins are unique to mammals. Many inhibit retrovirus infection through a cDNA cytosine deamination mechanism. HIV-1 neutralizes this host defense through Vif, which triggers APOBEC3 ubiquitination and degradation. Here, we report an APOBEC3F-like, double deaminase domain protein from...

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Detalles Bibliográficos
Autores principales:	Jónsson, Stefán R., Haché, Guylaine, Stenglein, Mark D., Fahrenkrug, Scott C., Andrésdóttir, Valgerdur, Harris, Reuben S.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2006
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636497/ https://www.ncbi.nlm.nih.gov/pubmed/17038330 http://dx.doi.org/10.1093/nar/gkl721

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