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Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcription

BACKGROUND: Transcription of HIV-1 genes is activated by HIV-1 Tat protein, which induces phosphorylation of RNA polymerase II (RNAPII) C-terminal domain (CTD) by CDK9/cyclin T1. Earlier we showed that CDK2/cyclin E phosphorylates HIV-1 Tat in vitro. We also showed that CDK2 induces HIV-1 transcript...

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Detalles Bibliográficos
Autores principales:	Ammosova, Tatyana, Berro, Reem, Jerebtsova, Marina, Jackson, Angela, Charles, Sharroya, Klase, Zachary, Southerland, William, Gordeuk, Victor R, Kashanchi, Fatah, Nekhai, Sergei
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636661/ https://www.ncbi.nlm.nih.gov/pubmed/17083724 http://dx.doi.org/10.1186/1742-4690-3-78

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